| Attribute | Description |
|---|---|
| Generic Name | Sildenafil Citrate |
| Dosage | 50 mg, 100 mg |
| Form | Oral Tablets |
| Manufacturer | Cipla Ltd. |
| Learn More | |
Chemical Structure
The active ingredient in Silagra, sildenafil citrate, is a member of the phosphodiesterase type 5 (PDE5) inhibitors class. Its molecular formula is C22H30N6O4S, featuring a complex heterocyclic structure. The crystalline solid appears as a white to off-white powder. The three-dimensional arrangement allows sildenafil to effectively bind and inhibit its target enzyme, critical for its therapeutic action.
Sildenafil’s structural backbone includes a piperazine ring, a core pyrazolopyrimidinone, and a sulfonamide group. The sulfonamide moiety is vital for selective PDE5 binding, a key feature setting sildenafil apart in its pharmacological profile. The lipophilic characteristics enhance its bioavailability, crucial for achieving the desired plasma concentration after administration.
Mechanism of Action
Silagra targets the PDE5 enzyme, predominantly located in the vascular tissues of the penis. Inhibition of PDE5 enhances cyclic guanosine monophosphate (cGMP) levels. This biochemical cascade results in smooth muscle relaxation, facilitating increased blood flow. Consequently, an erection occurs in response to sexual stimulation.
Sildenafil’s specificity for PDE5 over other phosphodiesterases minimizes off-target effects, ensuring its safety and efficacy. The increased cGMP leads to prolonged vascular relaxation, sustaining the erection necessary for satisfactory sexual activity. The mechanism of action underscores its therapeutic effectiveness for erectile dysfunction (ED).
FDA-Approved Indications
Silagra 100 mg is approved for treating erectile dysfunction. It addresses impotence issues arising from vascular, neurological, or psychological causes. As an oral medication, it offers convenience and discretion for users.
The use of Silagra extends beyond ED, with sildenafil also indicated for pulmonary arterial hypertension under the brand name Revatio. However, Silagra’s primary use remains in managing ED, with established safety and efficacy through rigorous clinical evaluations.
Silagra Disposal
Proper disposal of Silagra ensures environmental safety. Unused or expired tablets should not enter household waste or sewage systems. Instead, return them to a pharmacy for safe disposal.
If a return is not feasible, consult local waste management authorities for specific instructions. Responsible disposal safeguards against unintended exposure and environmental contamination.
Side Effects
Common side effects of Silagra 50 mg include headaches, flushing, and indigestion. These reactions are typically mild and transient. Vision disturbances, dizziness, and nasal congestion are also reported but occur less frequently.
Severe side effects, such as priapism, require immediate medical attention. Users must adhere to prescribed dosages and consult healthcare professionals for any adverse reactions. Balancing efficacy with safety is crucial for optimal therapeutic outcomes.
Silagra for Sale Online
The convenience of purchasing Silagra online appeals to many users. It offers discretion and easy access. However, users must ensure they are buying from reputable sources. Authenticity guarantees product safety and efficacy.
Users should verify online pharmacy credentials and consult healthcare providers before purchase. Counterfeit products pose health risks. Ensuring the legitimacy of the source is imperative for maintaining health and well-being.
- Effectiveness: High success rate for ED treatment.
- Accessibility: Widely available both online and offline.
- Affordability: Competitive pricing compared to brand-name counterparts.
Primary source:
- http://www.alloneaerosol.com/index.php/2024/07/15/afamelanotid-implanti-yuz-hemiatrofisi-icin-potansiyel-bir-tedavi-mi/
- https://www.pramhut.com/uveomeningoencephalitic-syndrome-a-new-perspective-on-prostate-cancer-treatment/
- https://tradesoluciones.com/2024/08/24/las-enfermedades-de-von-willebrand-y-sus-complejidades/
- https://cidaservices.com/explorando-a-interacao-uso-de-temazepam-no-complexo-de-eisenmenger/
- https://milleniumtradingcompanyltd.com/vector-borne-diseases-unveiling-the-link-with-vaccines-and-nutrition/
- https://cefacilinas.com/machado-joseph-disease-and-asthma-a-biochemical-insight/
- https://jncimmigration.ca/klippel-feil-syndrome-mechanisms-explored/
- https://oskarkern.com/fibroese-dysplasie-klinische-implikationen-und-behandlungsmoeglichkeiten/
- https://juliesanborn.ad-wize.net/landau-kleffner-syndrome-a-vascular-perspective/
- https://steedimmigration.com/exploring-links-deogestrel-ethinyl-estradiol-and-colorectal-cancer/
